Rizia Bardhan
Title(s):
Professor, Jean H. Steffenson Professor in Chemical and Biological Engineering
Office
5005 ATRB
2213 Pammel Dr.
Ames, IA 50011-1101
Information
Education
- Ph.D., Chemistry, Rice University, 2010
- B.A., Mathematics and Chemistry, Westminster College, Fulton, MO, 2005
Work Experience
- January 2021 – Associate Editor, ACS Applied Materials and Interfaces
- January, 2020 – Associate Professor, Department of Chemical and Biological Engineering, Iowa State University, Ames, IA
- 2012 – 2019 – Assistant Professor, Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN
- 2010 – 2012 – Postdoctoral Fellow, The Molecular Foundry, Lawrence Berkeley National Lab, Berkeley, CA
Research Interests My research group focuses on nanomedicine and nanophotonics. We design nanomaterials that can be activated with light (and other stimuli such as heat, pH etc.) and utilize them for bioimaging and therapies across many disease models including cancer, neurodegenerative disease, and infection. Current projects in my group include (1) imaging immunomarkers and response to immunotherapies (2) metabolic imaging with Raman spectroscopy for high throughput drug screening (3) examine how the mechanomolecular properties of nanomaterials impact their behavior in vitro and in vivo (4) combinatorial photothermal immunotherapies to induce antitumor immunity. (5) point-of-care biodiagnostics for rapid biomarker detection More information: https://faculty.sites.iastate.edu/rbardhan/
Publications
Y-C. Ou, X. Wen, C. A. Johnson, D. Shae, O. Ayala, J. A. Webb, E. C. Lin, R. C. DeLapp, K. L. Boyd, M. Rafat, A. Richmond, A. Mahadevan-Jansen, J. T. Wilson, J. M. Balko, M. N. Tantawy, A. E. Vilgelm, R. Bardhan*, “Multimodal Multiplexed Immunoimaging with Nanostars for Detection of both PD-L1 and CD8, and Monitoring Response to Immunotherapies”, ACS Nano, 2020, 14, 651 – 663. Y-C. Ou, X. Wen, R. Bardhan*, “Cancer Immunoimaging with Smart Nanoparticles”, Trends in Biotechnology, 2020, in press Y-C. Ou, J. A. Webb, C. M. O’Brien, I. Pence, E. C. Lin, E. P. Paul, D. Cole, S-H. Ou, M. Lapierre-Landry, E. S. Lippman, A. Mahadevan-Jansen, and R. Bardhan*, “Diagnosis of Immunomarkers in vivo via Multiplexed Surface Enhanced Raman Spectroscopy with Gold Nanostars “, Nanoscale, 2018, 10, 13092-13105 J.A. Webb#, Y-C. Ou#, S. Faley, E. P. Paul, J. P. Hittinger, C. C. Cutright, E. C. Lin, L. M. Bellan, and R. Bardhan*, “Theranostic Gold Nanoantennas for Simultaneous Multiplexed Raman Imaging of Immunomarkers and Photothermal Therapy”, ACS Omega, 2017, 2, 3583–3594. (# equal contributing first author) H. F.r Zarick, A. Boulesbaa, E. M. Talbert, A. Puretzky, D. Geohegan, and R. Bardhan*, “Ultrafast Excited-State Dynamics in Composition-Controlled Gold-Silver Bimetallic Nanostructures”, J. Phys. Chem. C, 2017, 121, 4540–4547. Y-C. Ou, J. A. Webb, S. Faley, D. Shae, E. M. Talbert, S. Lin, C. C. Cutright, J. T. Wilson, L. M. Bellan, and R. Bardhan*, “Gold Nanoantenna Mediated Photothermal Drug Delivery from Thermosensitive Liposomes in Breast Cancer”, ACS Omega, 2016, 1, 234–243 J. A. Webb, and R. Bardhan*, “Emerging Advances in Nanomedicine with Engineered Gold Nanostructures” Nanoscale, 2014, 6, 2502-2530 J.A. Webb, W. R. Erwin, H. F. Zarick, J. Aufrecht, H. Manning, M. J. Lang, C. L. Pint, R. Bardhan*, “Geometry Dependent Plasmonic Tunability and Photothermal Characteristics of Multibranched Gold Nanoantennas”, J. Physical Chemistry C, 2014, 118, 3696-3707 J.A.Webbu, J. Aufrecht, C. Hungerford, and R. Bardhan*, “Ultrasensitive Analyte Detection with Plasmonic Paper Dipsticks and Swabs Integrated with Branched Nanoantennas”, J. Materials Chemistry C, 2014, 2, 10446 – 10454
Primary Strategic Research Area
Engineered Medicine